Interactor 1: TERA (P46462)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: Vcp

Interactor 2: NPL4 (Q9ES54)
Nuclear protein localization protein 4 homolog (Protein NPL4)
Gene: Nploc4

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.715

The method score is based on:

Property Details
Experiments 10811609
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~NPL4, AAA~zf-NPL4, CDC48_2~UN_NPL4, CDC48_N~UN_NPL4
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0031625 - ubiquitin protein ligase binding
and 3 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 806
Rn

1 608
+ Mm
+ Hs
+ Xl
+ Dm
+ Sc
+ Sp

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Last updated: 15 Jul 2024