HitPredict

Interactor 1: CDN1B (P46527)
Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Gene: CDKN1B

Interactor 2: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	15057270
Identification Methods	pull down, affinity chromatography technology, unspecified method
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 538
+	Hs
		238643 CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00		IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48
+	Hs
		134849 CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00		IMA3_HUMAN (1-538): 7e-156: 456: 45.84
+	Hs
		168624 CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59
+	Hs
		131399 CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00		IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91
+	Hs
		804085 CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36
+	Xl
		1193352 Q91646_XENLA (14-190): 2.49e-51: 166: 26.00		Q7ZX00_XENLA (3-538): 1.83e-146: 433: 42.88
+	Xl
		1118097 Q91646_XENLA (14-190): 2.49e-51: 166: 26.00		Q4QR45_XENLA (1-538): 9.5e-141: 418: 42.94
+	Xl
		1012696 Q91646_XENLA (14-190): 2.49e-51: 166: 26.00		Q0VGW7_XENLA (1-538): 4.28e-140: 416: 42.19