HitPredict

Interactor 1: CDN1B (P46527)
Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Gene: CDKN1B

Interactor 2: CKS1 (P61024)
Cyclin-dependent kinases regulatory subunit 1 (CKS-1)
Gene: CKS1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.731

Property	Details
Experiments	19584057, 28514442, 12813041, 12140288, 33961781, 23910095
Identification Methods	affinity chromatography technology, enzymatic study, pull down, unspecified method, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0019901 - protein kinase binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 79
+	Hs
		706790 CDN1B_HUMAN (1-198): 1.46e-79: 237: 100.00		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01
+	Hs
		758171 CDN1A_HUMAN (17-167): 1.06e-46: 152: 27.10		CKS1_HUMAN (1-79): 9.36e-40: 127: 100.00
+	Hs
		706788 CDN1A_HUMAN (17-167): 1.06e-46: 152: 27.10		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01