Interactor 1: CDN1B (P46527)
Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Gene: CDKN1B

Interactor 2: CCNA1 (P78396)
Cyclin-A1
Gene: CCNA1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 29997244, 26264872, 33961781, 25483085, 16774918, 15583032, 18692475, 32814053
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology, pull down, luminescence based mammalian interactome mapping, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDI~Cyclin_N
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 198
Hs

1 465
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Xl
+ Xl
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024