HitPredict

Interactor 1: CDN1B (P46527)
Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Gene: CDKN1B

Interactor 2: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

The method score is based on:

Property	Details
Experiments	16189514, 31515488, 25910212
Identification Methods	two hybrid, two hybrid array, two hybrid bait and prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0019903 - protein phosphatase binding and 3 others more... GO:0031625 - ubiquitin protein ligase binding GO:0044877 - protein-containing complex binding GO:0060090 - molecular adaptor activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	198
Hs

1	501

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024