Interactor 1: CDN1B (P46527)
Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Gene: CDKN1B
Interactor 2: SKP2 (Q13309)
S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2)
Gene: SKP2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.60 | 0.769 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21503567, 26450989, 12042314, 33854235, 35247157, 15735731, 15469821, 21237244, 20160482, 15355997, 10559916, 18239684, 23910095, 20663873, 22959436, 22524983, 19112177, 23911321, 29137415, 27565346 and 13 others
more... |
| Identification Methods | affinity chromatography technology, unspecified method, enzymatic study, pull down, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000082 - G1/S transition of mitotic cell cycle GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0051726 - regulation of cell cycle |
| Homologous interactions | 7 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
