Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Interactor 2: HMGN5 (P82970)
High mobility group nucleosome-binding domain-containing protein 5 (Nucleosome-binding protein 1)
Gene: HMGN5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 27229929
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription
GO:0008284 - positive regulation of cell population proliferation
GO:0010628 - positive regulation of gene expression
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 2555
Hs

1 282
+ Hs

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Last updated: 15 Jul 2024