Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1
Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8642313 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank~RHD_dimer, Ank_2~RHD_dimer |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001889 - liver development GO:0005634 - nucleus GO:0005654 - nucleoplasm and 12 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
