HitPredict

Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~fn3, EGF_CA~fn3
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2555 Hs			1 783
+	Hs
		262156 NOTC1_HUMAN (20-2555): 0: 1387: 100.00		TRIM3_HUMAN (190-767): 1.26e-78: 270: 15.01
+	Hs
		965126 ANK2_HUMAN (1662-2151): 4.82e-101: 367: 16.67		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1021420 ANK3_HUMAN (1572-2114): 5.09e-98: 358: 17.60		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172237 ANR50_HUMAN (1862-2553): 1.06e-91: 332: 15.85		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		556708 ANK1_HUMAN (1963-2550): 1.92e-90: 331: 12.75		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1170718 ANKH1_HUMAN (1617-2544): 8.61e-80: 297: 12.51		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		257636 ANR17_HUMAN (1919-2553): 8.85e-80: 297: 13.87		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1170824 ANR44_HUMAN (1554-2093): 7.06e-68: 252: 15.72		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1170834 ANR52_HUMAN (1998-2492): 2.36e-64: 242: 13.80		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		944121 JAG1_HUMAN (8-429): 2.99e-40: 166: 25.26		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		724379 FBN2_HUMAN (573-1697): 5.09e-30: 133: 15.09		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		624333 TENA_HUMAN (1356-1565): 3.2e-18: 94.5: 20.94		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1126605 CRUM2_HUMAN (12-142): 2.04e-11: 72.2: 32.61		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		724374 FBN2_HUMAN (573-1697): 5.09e-30: 133: 15.09		TRI68_HUMAN (200-776): 1.52e-87: 286: 13.42
+	Hs
		1059068 LTBP2_HUMAN (4-596): 1.9e-24: 115: 20.27		TRI68_HUMAN (200-776): 1.52e-87: 286: 13.42
+	Hs
		1052704 ANKH1_HUMAN (1617-2544): 8.61e-80: 297: 12.51		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29