Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Interactor 2: LNX2 (Q8N448)
Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1)
Gene: LNX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 27229929
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 2555
Hs

1 690
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Dm
+ Ce
+ Hs
+ Ce

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Last updated: 15 Jul 2024