HitPredict

Interactor 1: MP2K3 (P46734)
Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)
Gene: MAP2K3

Interactor 2: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38113892
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 347 Hs			1 183
+	Hs
		682160 AKT2_HUMAN (38-345): 6.46e-126: 371: 22.79		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Dm
		532277 KPC3_DROME (1-345): 9.62e-122: 368: 19.77		Q9VQ00_DROME (4-152): 3.9e-64: 196: 26.14
+	Zm
		8408 Q6RXY1_MAIZE (63-347): 1.8e-114: 343: 23.02		A0A1D6ENM7_MAIZE (4-151): 8e-73: 218: 29.61
+	Hs
		647861 MARK3_HUMAN (8-344): 6.23e-120: 364: 19.53		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		908733 MARK2_HUMAN (8-344): 2.1e-119: 364: 20.41		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Dm
		715095 AKT1_DROME (58-345): 1.06e-122: 367: 20.95		UBE2N_DROME (5-152): 6.43e-62: 190: 34.21
+	Hs
		625230 CDK2_HUMAN (61-336): 3.55e-114: 335: 23.43		UBE2A_HUMAN (4-150): 8.87e-65: 197: 30.46
+	Hs
		625305 CDK2_HUMAN (61-336): 3.55e-114: 335: 23.43		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		908460 STK4_HUMAN (42-345): 1.62e-103: 314: 33.12		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00