Interactor 1: BRCC3 (P46736)
Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36)
Gene: BRCC3

Interactor 2: ABRX2 (Q15018)
BRISC complex subunit Abraxas 2 (Abraxas brother protein 1) (Protein FAM175B)
Gene: ABRAXAS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.759

The method score is based on:

Property Details
Experiments 25283148, 26186194, 26195665, 28514442, 24075985, 30755420, 31142841, 33961781, 21282113, 20656690, 33107021, 35235311, 19615732, 20032457
Identification Methods affinity chromatography technology, cross-linking study, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000922 - spindle pole
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031593 - polyubiquitin modification-dependent protein binding
and 3 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 316
Hs

1 415
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024