Interactor 1: BRCC3 (P46736)
Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36)
Gene: BRCC3

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 19214193
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCC36_C~JAB, CSN5_C~JAB, JAB~JAB
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 316
Hs

1 334
+ Hs
+ Hs
+ Ce
+ Zm
+ Hs
+ Ce
+ Dm
+ Sc
+ Hs
+ Sp
+ Ce
+ Zm
+ Hs
+ At
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024