HitPredict - High confidence protein-protein interactions

Interactor 1: RL5 (P46777)
Large ribosomal subunit protein uL18 (60S ribosomal protein L5)
Gene: RPL5

Interactor 2: RL23 (P62829)
Large ribosomal subunit protein uL14 (60S ribosomal protein L17) (60S ribosomal protein L23)
Gene: RPL23

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	30021884, 35271311, 15308643, 17116689, 36652389
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002181 - cytoplasmic translation GO:0003723 - RNA binding GO:0003735 - structural constituent of ribosome GO:0005654 - nucleoplasm GO:0005730 - nucleolus and 15 others more... GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0006412 - translation GO:0010628 - positive regulation of gene expression GO:0016020 - membrane GO:0022625 - cytosolic large ribosomal subunit GO:0022626 - cytosolic ribosome GO:0031625 - ubiquitin protein ligase binding GO:0032991 - protein-containing complex GO:0050821 - protein stabilization GO:0070062 - extracellular exosome GO:1904667 - negative regulation of ubiquitin protein ligase activity GO:1990948 - ubiquitin ligase inhibitor activity GO:2000059 - negative regulation of ubiquitin-dependent protein catabolic process
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	297
Hs

1	140

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024