HitPredict - High confidence protein-protein interactions

Interactor 1: RL5 (P46777)
Large ribosomal subunit protein uL18 (60S ribosomal protein L5)
Gene: RPL5

Interactor 2: RL11 (P62913)
Large ribosomal subunit protein uL5 (60S ribosomal protein L11) (CLL-associated antigen KW-12)
Gene: RPL11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	1.00	0.964

Property	Details
Experiments	35271311, 37071682, 15308643, 17116689, 23169665, 33961781, 36652389, 18560357
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ribosomal_L5_C~Ribosomal_L5e
Common GO terms	GO:0000027 - ribosomal large subunit assembly GO:0002181 - cytoplasmic translation GO:0003723 - RNA binding GO:0003735 - structural constituent of ribosome GO:0005654 - nucleoplasm and 20 others more... GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006364 - rRNA processing GO:0006412 - translation GO:0008097 - 5S rRNA binding GO:0010628 - positive regulation of gene expression GO:0016020 - membrane GO:0022625 - cytosolic large ribosomal subunit GO:0022626 - cytosolic ribosome GO:0031625 - ubiquitin protein ligase binding GO:0032991 - protein-containing complex GO:0042273 - ribosomal large subunit biogenesis GO:0050821 - protein stabilization GO:0070062 - extracellular exosome GO:1901796 - regulation of signal transduction by p53 class mediator GO:1904667 - negative regulation of ubiquitin protein ligase activity GO:1990948 - ubiquitin ligase inhibitor activity GO:2000059 - negative regulation of ubiquitin-dependent protein catabolic process GO:2000435 - negative regulation of protein neddylation
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	297
Hs

1	178

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024