HitPredict

Interactor 1: MAP1B (P46821)
Microtubule-associated protein 1B (MAP-1B) [Cleaved into: MAP1B heavy chain; MAP1 light chain LC1]
Gene: MAP1B

Interactor 2: HSPB8 (Q9UJY1)
Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (E2-induced gene 1 protein) (Heat shock protein family B member 8) (Protein kinase H11) (Small stress protein-like protein HSP22)
Gene: HSPB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2468 Hs			1 196
+	Hs
		388295 MAP1B_HUMAN (1-2468): 0: 950: 100.00		HSPB1_HUMAN (1-179): 9.77e-63: 194: 36.67
+	Hs
		358986 MAP1B_HUMAN (1-2468): 0: 950: 100.00		CRYAB_HUMAN (6-187): 3.08e-53: 169: 31.69
+	Hs
		147846 MAP1B_HUMAN (1-2468): 0: 950: 100.00		HSPB6_HUMAN (5-166): 4.57e-44: 146: 31.10
+	Hs
		1264819 TITIN_HUMAN (362-1320): 1.1e-10: 69.8: 8.51		HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00
+	Dm
		359181 NBEA_DROME (541-1271): 6.22e-16: 87.4: 13.60		HSP23_DROME (30-193): 7.8e-48: 156: 25.61
+	Hs
		359052 TITIN_HUMAN (362-1320): 1.1e-10: 69.8: 8.51		CRYAB_HUMAN (6-187): 3.08e-53: 169: 31.69
+	Hs
		1080881 TITIN_HUMAN (362-1320): 1.1e-10: 69.8: 8.51		HSPB2_HUMAN (1-170): 5.01e-42: 141: 25.88