Interactor 1: NEDD4 (P46934)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 24981860, 36931259
Identification Methods affinity chromatography technology, tandem affinity purification, cross-linking study
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019899 - enzyme binding
GO:0019904 - protein domain specific binding
and 3 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1319
Hs

1 255
+ Mm
+ Hs
+ Mm
+ Hs
+ At
+ Sc
+ Sc
+ Hs
+ Rn
+ Sc
+ Sc
+ Mm

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Last updated: 15 Jul 2024