HitPredict

Interactor 1: NEDD4 (P46934)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1319 Hs			1 783
+	Hs
		1171305 NED4L_HUMAN (517-1319): 0: 934: 62.26		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1170603 HUWE1_HUMAN (799-1317): 6.4e-169: 562: 35.32		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Mm
		1186495 HUWE1_MOUSE (799-1317): 8.82e-169: 561: 35.25		TRIM3_MOUSE (190-767): 6.68e-78: 268: 14.85
+	Hs
		1171253 ITCH_HUMAN (468-799): 2.73e-28: 125: 19.42		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1171774 SMUF2_HUMAN (454-719): 3.19e-26: 118: 17.86		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1171800 SMUF1_HUMAN (539-719): 7.11e-18: 91.8: 16.82		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1052695 HUWE1_HUMAN (799-1317): 6.4e-169: 562: 35.32		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29
+	Hs
		262198 HECW2_HUMAN (434-992): 3.07e-10: 67.1: 13.83		TRIM3_HUMAN (190-767): 1.26e-78: 270: 15.01
+	Hs
		125454 WWP2_HUMAN (461-817): 1.56e-41: 167: 17.91		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29
+	Hs
		1290890 SMUF1_HUMAN (539-719): 7.11e-18: 91.8: 16.82		TRI11_HUMAN (1-121): 1.6e-09: 63.2: 20.66
+	Hs
		1052789 HECW2_HUMAN (434-992): 3.07e-10: 67.1: 13.83		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29