HitPredict

Interactor 1: NEDD4 (P46934)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Interactor 2: TS101 (Q99816)
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
Gene: TSG101

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 36642186, 16138902
Identification Methods x-ray crystallography, affinity chromatography technology
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0043130 - ubiquitin binding
and 3 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1319
Hs

1 390
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024