HitPredict

Interactor 1: NEDD4 (P46934)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Interactor 2: CUED1 (Q9NWM3)
CUE domain-containing protein 1
Gene: CUEDC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	19953087
Identification Methods	enzymatic study, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043130 - ubiquitin binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1319 Hs			1 386
+	Hs
		1299649 NED4L_HUMAN (517-1319): 0: 934: 62.26		CUED1_HUMAN (1-386): 0: 606: 100.00
+	Hs
		1327924 WWP1_HUMAN (389-800): 7.48e-49: 191: 17.86		CUED1_HUMAN (1-386): 0: 606: 100.00
+	Hs
		1294873 ITCH_HUMAN (468-799): 2.73e-28: 125: 19.42		CUED1_HUMAN (1-386): 0: 606: 100.00
+	Hs
		1334875 SMUF2_HUMAN (454-719): 3.19e-26: 118: 17.86		CUED1_HUMAN (1-386): 0: 606: 100.00
+	Hs
		1336093 SMUF1_HUMAN (539-719): 7.11e-18: 91.8: 16.82		CUED1_HUMAN (1-386): 0: 606: 100.00
+	Hs
		1347233 HECW2_HUMAN (434-992): 3.07e-10: 67.1: 13.83		CUED1_HUMAN (1-386): 0: 606: 100.00