HitPredict

Interactor 1: NEDD4 (P46935)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Interactor 2: NFIP1 (Q8R0W6)
NEDD4 family-interacting protein 1 (NEDD4 WW domain-binding protein 5)
Gene: Ndfip1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 11042109, 11748237, 22417925, 18819914
Identification Methods far western blotting, affinity chromatography technology, anti tag coimmunoprecipitation, affinity technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016020 - membrane
GO:0045732 - positive regulation of protein catabolic process
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 887
Mm

1 221
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024