HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: HSP72 (P54652)
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) (Heat shock protein family A member 2)
Gene: HSPA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	33961781, 31501420, 26933062
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 639
+	Hs
		125115 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		HSP7C_HUMAN (3-616): 0: 946: 87.95
+	Hs
		504580 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		HSP7C_HUMAN (3-616): 0: 946: 87.95
+	Hs
		713923 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		HS71L_HUMAN (2-639): 0: 953: 81.90
+	Hs
		504792 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		HSP7C_HUMAN (3-616): 0: 946: 87.95
+	Hs
		503644 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		HSP7C_HUMAN (3-616): 0: 946: 87.95
+	Hs
		564032 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		HSP76_HUMAN (2-639): 0: 945: 77.45
+	Hs
		564179 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		HSP76_HUMAN (2-639): 0: 945: 77.45
+	Hs
		504871 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		HSP7C_HUMAN (3-616): 0: 946: 87.95