HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: IF4A1 (P60842)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Gene: EIF4A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31501420
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 406
+	Hs
		125142 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88
+	Hs
		125617 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33
+	Hs
		125203 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		IF4A3_HUMAN (1-406): 1.93e-134: 393: 66.75
+	Hs
		125295 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		IF4A1_HUMAN (1-406): 1.84e-132: 387: 100.00
+	Hs
		571603 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88
+	Hs
		571348 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88
+	Hs
		808816 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33
+	Mm
		809069 YAP1_MOUSE (35-504): 1.41e-115: 351: 91.70		DDX17_MOUSE (2-406): 1.38e-137: 409: 29.33
+	Hs
		757756 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		IF4A3_HUMAN (1-406): 1.93e-134: 393: 66.75
+	Hs
		125164 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		DDX6_HUMAN (32-402): 1.66e-88: 278: 38.71
+	Sc
		485815 TOM1_YEAST (261-504): 2.18e-46: 176: 11.34		IF4A_YEAST (20-406): 8.01e-168: 477: 66.41
+	Sc
		761942 RSP5_YEAST (3-504): 1.79e-105: 334: 15.25		DHH1_YEAST (32-402): 1.41e-99: 307: 44.47
+	Hs
		640364 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		DDX6_HUMAN (32-402): 1.66e-88: 278: 38.71
+	Hs
		1271653 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33
+	Sc
		624167 TOM1_YEAST (261-504): 2.18e-46: 176: 11.34		DBP2_YEAST (2-404): 8.49e-137: 403: 31.63
+	Hs
		1271684 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33
+	Hs
		757781 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		IF4A3_HUMAN (1-406): 1.93e-134: 393: 66.75
+	Hs
		640646 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		DDX6_HUMAN (32-402): 1.66e-88: 278: 38.71