HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30472188, 31501420, 38280479
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016020 - membrane GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 463
+	Hs
		125311 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Hs
		904148 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Hs
		904128 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Hs
		808075 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Hs
		125473 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21
+	Hs
		125622 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29
+	Hs
		125472 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15
+	Hs
		125820 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00
+	Hs
		125765 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		IF2B1_HUMAN (175-462): 1.88e-09: 62: 11.57
+	Hs
		1072159 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21
+	Hs
		1072029 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15
+	Hs
		1072012 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15
+	Hs
		808629 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21
+	Hs
		808819 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29
+	Hs
		808628 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15
+	Hs
		808828 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		FUBP1_HUMAN (300-460): 2.19e-09: 61.6: 19.64
+	Hs
		1283851 SMUF2_HUMAN (99-504): 4.95e-107: 337: 19.19		FUBP1_HUMAN (300-460): 2.19e-09: 61.6: 19.64
+	Hs
		1273064 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29
+	Hs
		1072008 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15
+	Hs
		128324 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		IF2B3_HUMAN (272-463): 9e-09: 59.7: 14.57