HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	24255178, 24366813, 25796446, 27684187, 25751139
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 330
+	Hs
		125313 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Hs
		125314 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		737645 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		808455 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		931006 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		PP2AA_HUMAN (8-302): 3.14e-176: 492: 47.30
+	Hs
		808496 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PP2AA_HUMAN (8-302): 3.14e-176: 492: 47.30
+	Hs
		906120 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Hs
		906167 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		PP1A_HUMAN (1-330): 0: 614: 100.00