HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 89
+	Hs
		125641 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		808839 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		928459 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		928377 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		928338 WWC2_HUMAN (163-315): 3.48e-35: 142: 24.18		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		1220076 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		1149654 WWC2_HUMAN (163-315): 3.48e-35: 142: 24.18		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26