HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25796446, 38280479
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 2115
+	Hs
		125464 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061257 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061238 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		724701 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		725106 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34
+	Hs
		808624 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		728454 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		MYH11_HUMAN (1430-2076): 4.75e-22: 107: 8.41
+	Hs
		518833 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04
+	Hs
		1220103 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		MYH4_HUMAN (1-831): 9.18e-34: 145: 12.50
+	Hs
		522650 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		MYH7_HUMAN (947-2023): 1.11e-36: 155: 11.21
+	Hs
		522575 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		MYH1_HUMAN (1-831): 3.6e-35: 150: 12.27
+	Hs
		1349059 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		MYH4_HUMAN (1-831): 9.18e-34: 145: 12.50
+	Sc
		630972 TOM1_YEAST (261-504): 2.18e-46: 176: 11.34		USO1_YEAST (867-1693): 9.79e-11: 69.7: 18.63
+	Hs
		828634 HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79		CENPF_HUMAN (1458-2037): 1.6e-10: 69.3: 9.97