HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: TEAD2 (Q15562)
Transcriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2)
Gene: TEAD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 28205554, 26578655, 25973055, 28514442, 32296183, 33961781, 35140242, 20368466, 25751139, unassigned1304
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology, two hybrid, proximity labelling technology, nuclear magnetic resonance, isothermal titration calorimetry, pull down, tandem affinity purification, anti tag coimmunoprecipitation, validated two hybrid and 2 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001570 - vasculogenesis
GO:0003143 - embryonic heart tube morphogenesis
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 10 others

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Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Last updated: 15 Jul 2024