HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: GGYF2 (Q6Y7W6)
GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein)
Gene: GIGYF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0070064 - proline-rich region binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 1299
+	Hs
		125532 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		GGYF2_HUMAN (1-1299): 4.85e-105: 364: 100.00
+	Hs
		125768 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		RRBP1_HUMAN (111-1298): 2.09e-49: 194: 10.49
+	Hs
		808430 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		AFAD_HUMAN (299-880): 8.47e-55: 212: 16.30
+	Hs
		1327928 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		RRBP1_HUMAN (111-1298): 2.09e-49: 194: 10.49
+	Hs
		808977 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		RRBP1_HUMAN (111-1298): 2.09e-49: 194: 10.49
+	Hs
		1167957 MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32		GGYF2_HUMAN (1-1299): 4.85e-105: 364: 100.00
+	Hs
		728454 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		MYH11_HUMAN (705-1294): 1.67e-26: 120: 9.81
+	Hs
		725106 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		MYH10_HUMAN (351-1292): 8.75e-26: 118: 10.28
+	Hs
		1078893 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		ITSN1_HUMAN (767-1126): 1.03e-17: 91.7: 16.62
+	Hs
		724701 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Hs
		1035209 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		ROCK1_HUMAN (649-1271): 9.18e-17: 88.6: 12.04
+	Hs
		808624 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PLEC_HUMAN (324-1292): 6.24e-14: 79.4: 8.88
+	Hs
		808731 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		MYH14_HUMAN (719-1022): 6.74e-10: 66.2: 19.94
+	Hs
		808919 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		SLK_HUMAN (753-1031): 1.3e-09: 65: 17.39
+	Hs
		264381 MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32		GGYF1_HUMAN (1-619): 2.01e-71: 261: 46.64
+	Hs
		876499 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		AFAD_HUMAN (299-880): 8.47e-55: 212: 16.30
+	Hs
		876475 MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32		AFAD_HUMAN (299-880): 8.47e-55: 212: 16.30
+	Hs
		1326735 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		SLK_HUMAN (753-1031): 1.3e-09: 65: 17.39
+	Hs
		1220103 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		MYH4_HUMAN (718-1299): 2.11e-19: 97.5: 11.47
+	Hs
		522575 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		MYH1_HUMAN (719-1299): 3.77e-20: 99.8: 11.49