HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: K2C74 (Q7RTS7)
Keratin, type II cytoskeletal 74 (Cytokeratin-74) (CK-74) (Keratin-5c) (K5C) (Keratin-74) (K74) (Type II inner root sheath-specific keratin-K6irs4) (Type-II keratin Kb37)
Gene: KRT74

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 529
+	Hs
		380579 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		K2C1_HUMAN (105-471): 4.75e-164: 481: 66.21
+	Hs
		808737 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		K2C1B_HUMAN (45-471): 3.4e-110: 341: 57.27
+	Hs
		808745 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		K2C73_HUMAN (1-456): 4.65e-105: 326: 79.43
+	Hs
		318788 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		K2C75_HUMAN (1-465): 1.1e-95: 302: 58.49
+	Hs
		808667 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		K2C71_HUMAN (1-456): 4.23e-91: 290: 78.99
+	Hs
		808688 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		K2C79_HUMAN (17-470): 6e-86: 277: 58.11
+	Hs
		380449 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		K2C6B_HUMAN (8-472): 3.98e-81: 265: 57.00
+	Hs
		359472 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		K2C6A_HUMAN (8-472): 9.42e-78: 256: 57.20
+	Hs
		808524 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		K22O_HUMAN (1-468): 9e-70: 237: 56.95
+	Hs
		280825 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		KRT36_HUMAN (18-519): 8.08e-67: 225: 21.91
+	Hs
		517789 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		K2C3_HUMAN (88-458): 4.88e-147: 437: 66.49
+	Hs
		1192450 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		K2C1B_HUMAN (45-471): 3.4e-110: 341: 57.27
+	Hs
		1055221 MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32		KRT81_HUMAN (6-453): 7.89e-95: 299: 45.58
+	Hs
		318896 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		K2C75_HUMAN (1-465): 1.1e-95: 302: 58.49
+	Hs
		821682 MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32		K2C6C_HUMAN (8-472): 1.23e-80: 264: 57.00
+	Hs
		380499 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		K2C6B_HUMAN (8-472): 3.98e-81: 265: 57.00
+	Hs
		821676 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		K2C6C_HUMAN (8-472): 1.23e-80: 264: 57.00
+	Hs
		580143 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		K2C4_HUMAN (10-472): 1.35e-74: 247: 63.09