HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: PALS1 (Q8N3R9)
Protein PALS1 (MAGUK p55 subfamily member 5) (Membrane protein, palmitoylated 5) (Protein associated with Lin-7 1)
Gene: PALS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

Property	Details
Experiments	28514442, 33961781, 24366813, 25796446, 27684187, 30472188, 38280479, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 675
+	Hs
		125577 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PALS1_HUMAN (1-675): 0: 561: 100.00
+	Hs
		1232500 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		PALS1_HUMAN (1-675): 0: 561: 100.00
+	Mm
		809081 YAP1_MOUSE (35-504): 1.41e-115: 351: 91.70		PALS1_MOUSE (1-675): 0: 559: 96.74
+	Hs
		808185 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		PALS1_HUMAN (1-675): 0: 561: 100.00
+	Mm
		93267 E9PXB7_MOUSE (8-504): 1.1e-114: 359: 19.11		DLG3_MOUSE (7-671): 2.7e-135: 419: 21.36
+	Mm
		808344 NEDD4_MOUSE (28-504): 2.4e-113: 357: 16.98		DLG3_MOUSE (7-671): 2.7e-135: 419: 21.36
+	Mm
		1143429 NED4L_MOUSE (4-504): 5.54e-115: 364: 19.73		DLG4_MOUSE (7-671): 3.43e-130: 402: 20.84
+	Hs
		1232499 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		PALS1_HUMAN (1-675): 0: 561: 100.00
+	Hs
		808565 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		DLG1_HUMAN (7-672): 1.81e-129: 406: 21.58
+	Mm
		93273 E9PXB7_MOUSE (8-504): 1.1e-114: 359: 19.11		DLG4_MOUSE (7-671): 3.43e-130: 402: 20.84
+	Mm
		1322235 WWTR1_MOUSE (39-504): 9.89e-56: 193: 38.90		PALS1_MOUSE (1-675): 0: 559: 96.74
+	Hs
		1232496 MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32		PALS1_HUMAN (1-675): 0: 561: 100.00
+	Hs
		1220066 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		PALS1_HUMAN (1-675): 0: 561: 100.00
+	Hs
		1232512 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		PALS1_HUMAN (1-675): 0: 561: 100.00
+	Hs
		1021560 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		DLG1_HUMAN (7-672): 1.81e-129: 406: 21.58
+	Mm
		1143518 MAGI3_MOUSE (69-287): 5.09e-40: 156: 21.68		DLG4_MOUSE (7-671): 3.43e-130: 402: 20.84
+	Hs
		1021531 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		DLG1_HUMAN (7-672): 1.81e-129: 406: 21.58
+	Hs
		1132878 KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27		MPP7_HUMAN (122-674): 6.17e-127: 389: 36.06
+	Hs
		1271021 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		DLG3_HUMAN (256-326): 7.18e-12: 70.8: 20.25