HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: ARRD1 (Q8N5I2)
Arrestin domain-containing protein 1 (Alpha-arrestin 1)
Gene: ARRDC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	29416926, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 433
+	Hs
		125580 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		ARRD1_HUMAN (1-433): 5.38e-131: 386: 100.00
+	Hs
		1234600 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		ARRD1_HUMAN (1-433): 5.38e-131: 386: 100.00
+	Hs
		1234602 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		ARRD1_HUMAN (1-433): 5.38e-131: 386: 100.00
+	Hs
		1234609 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		ARRD1_HUMAN (1-433): 5.38e-131: 386: 100.00
+	Hs
		1234607 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		ARRD1_HUMAN (1-433): 5.38e-131: 386: 100.00
+	Hs
		125595 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		ARRD2_HUMAN (2-371): 6.72e-95: 293: 22.36
+	Hs
		125633 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		ARRD3_HUMAN (1-373): 1.85e-94: 292: 20.81
+	Hs
		1252807 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		ARRD2_HUMAN (2-371): 6.72e-95: 293: 22.36
+	Hs
		1285047 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		ARRD3_HUMAN (1-373): 1.85e-94: 292: 20.81
+	Hs
		125707 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		TXNIP_HUMAN (3-360): 7.93e-86: 269: 21.09
+	Hs
		125586 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		ARRD4_HUMAN (2-361): 1.4e-82: 261: 24.07
+	Hs
		1252808 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		ARRD2_HUMAN (2-371): 6.72e-95: 293: 22.36
+	Hs
		1285052 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		ARRD3_HUMAN (1-373): 1.85e-94: 292: 20.81
+	Hs
		1294858 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		TXNIP_HUMAN (3-360): 7.93e-86: 269: 21.09
+	Hs
		1241904 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		ARRD4_HUMAN (2-361): 1.4e-82: 261: 24.07
+	Hs
		1299631 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		TXNIP_HUMAN (3-360): 7.93e-86: 269: 21.09
+	Hs
		1241907 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		ARRD4_HUMAN (2-361): 1.4e-82: 261: 24.07
+	Hs
		686035 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		ARRB2_HUMAN (22-320): 9.21e-72: 233: 16.62
+	Hs
		827260 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		ARRB1_HUMAN (22-339): 5.08e-70: 229: 15.29
+	Mm
		1208049 ITCH_MOUSE (2-504): 2.6e-119: 372: 14.36		ARRB2_MOUSE (22-320): 2.4e-69: 227: 16.29