HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: ENAH (Q8N8S7)
Protein enabled homolog
Gene: ENAH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	10358088, 30472188, 38280479
Identification Methods	pull down, affinity chromatography technology, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030054 - cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 591
+	Hs
		1336091 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		HOME2_HUMAN (1-299): 1.95e-65: 219: 18.75
+	Hs
		1191583 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		SPRE1_HUMAN (2-314): 1.71e-57: 201: 18.58
+	Hs
		125001 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		HGS_HUMAN (90-385): 6.31e-28: 120: 22.22
+	Hs
		1233533 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		MINK1_HUMAN (113-575): 1.26e-34: 142: 15.12
+	Hs
		808746 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		HOME1_HUMAN (1-285): 2.84e-39: 149: 15.64
+	Hs
		125448 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		EIF3A_HUMAN (89-278): 2e-23: 107: 21.15
+	Hs
		1078893 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		ITSN1_HUMAN (124-263): 2.96e-29: 125: 37.59
+	Mm
		949373 NED4L_MOUSE (4-504): 5.54e-115: 364: 19.73		TNIK_MOUSE (90-575): 1.04e-33: 139: 14.08
+	Hs
		160143 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		HGS_HUMAN (90-385): 6.31e-28: 120: 22.22
+	Mm
		93268 E9PXB7_MOUSE (8-504): 1.1e-114: 359: 19.11		TNIK_MOUSE (90-575): 1.04e-33: 139: 14.08
+	Mm
		808345 NEDD4_MOUSE (28-504): 2.4e-113: 357: 16.98		TNIK_MOUSE (90-575): 1.04e-33: 139: 14.08
+	Hs
		1336112 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		TNIK_HUMAN (129-587): 5.09e-30: 128: 17.86
+	Hs
		125250 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		VASP_HUMAN (263-590): 7.68e-20: 93.6: 29.18
+	Hs
		160160 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		HGS_HUMAN (90-385): 6.31e-28: 120: 22.22
+	Hs
		1049652 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		EIF3A_HUMAN (89-278): 2e-23: 107: 21.15
+	Hs
		808315 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		TNIK_HUMAN (129-587): 5.09e-30: 128: 17.86
+	Hs
		808598 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		EIF3A_HUMAN (89-278): 2e-23: 107: 21.15
+	Hs
		159925 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		HGS_HUMAN (90-385): 6.31e-28: 120: 22.22
+	Hs
		808404 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		VASP_HUMAN (263-590): 7.68e-20: 93.6: 29.18
+	Hs
		808990 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		SWP70_HUMAN (84-269): 5.97e-14: 76.9: 25.00