HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: RASF8 (Q8NHQ8)
Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1)
Gene: RASSF8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.50	0.617

Property	Details
Experiments	27684187, 30472188, 26933062, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 419
+	Hs
		125441 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		ASPP2_HUMAN (1-406): 1.62e-99: 322: 15.46
+	Hs
		1043731 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		ASPP2_HUMAN (1-406): 1.62e-99: 322: 15.46
+	Hs
		125654 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		ASPP1_HUMAN (1-399): 4.08e-87: 288: 14.99
+	Hs
		808586 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		ASPP2_HUMAN (1-406): 1.62e-99: 322: 15.46
+	Hs
		808118 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		ASPP2_HUMAN (1-406): 1.62e-99: 322: 15.46
+	Hs
		808529 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		RASF7_HUMAN (1-405): 1.95e-77: 246: 33.42
+	Hs
		808103 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		Q05BL1_HUMAN (84-406): 4.4e-64: 224: 12.16
+	Hs
		1043750 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		ASPP2_HUMAN (1-406): 1.62e-99: 322: 15.46
+	Hs
		1296373 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		ASPP1_HUMAN (1-399): 4.08e-87: 288: 14.99
+	Dm
		1362201 Q9W2L2_DROME (1-267): 6.8e-44: 168: 21.01		Q9VBP2_DROME (1-81): 8.78e-28: 117: 69.14
+	Dm
		1376443 Q9W2L2_DROME (1-267): 6.8e-44: 168: 21.01		Q9W2J2_DROME (137-336): 1.06e-10: 65.8: 9.35