HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: THOC2 (Q8NI27)
THO complex subunit 2 (Tho2) (hTREX120)
Gene: THOC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000902 - cell morphogenesis GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 1593
+	Hs
		125448 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		EIF3A_HUMAN (1140-1576): 5.31e-14: 79.9: 7.47
+	Hs
		1299627 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		NSRP1_HUMAN (1117-1593): 4.93e-24: 110: 9.33
+	Hs
		125249 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		YLPM1_HUMAN (1134-1593): 5.81e-11: 69.9: 9.62
+	Hs
		808264 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		NSRP1_HUMAN (1117-1593): 4.93e-24: 110: 9.33
+	Hs
		1049652 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		EIF3A_HUMAN (1140-1576): 5.31e-14: 79.9: 7.47
+	Hs
		1294841 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		MINT_HUMAN (1106-1593): 3.62e-09: 64.1: 9.78
+	Hs
		808598 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		EIF3A_HUMAN (1140-1576): 5.31e-14: 79.9: 7.47
+	Hs
		1191718 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		RBBP6_HUMAN (1129-1593): 1.23e-11: 72.2: 12.29
+	Dm
		1373179 SUDX_DROME (16-504): 4.46e-109: 347: 15.74		Q9VRM6_DROME (1063-1467): 2.38e-15: 84.5: 14.01
+	Hs
		808734 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		RBBP6_HUMAN (1129-1593): 1.23e-11: 72.2: 12.29
+	Hs
		808780 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		BD1L1_HUMAN (1140-1593): 4.25e-11: 70.7: 15.84
+	Hs
		808398 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		YLPM1_HUMAN (1134-1593): 5.81e-11: 69.9: 9.62
+	Hs
		808869 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		MINT_HUMAN (1106-1593): 3.62e-09: 64.1: 9.78
+	Dm
		54898 SUDX_DROME (16-504): 4.46e-109: 347: 15.74		A1ZA72_DROME (1106-1578): 5.88e-12: 73.4: 11.50
+	Dm
		54872 YAP1_DROME (52-268): 1.16e-44: 163: 29.25		A1ZA72_DROME (1106-1578): 5.88e-12: 73.4: 11.50
+	Hs
		1049665 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		EIF3A_HUMAN (1140-1576): 5.31e-14: 79.9: 7.47
+	Hs
		833047 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		YLPM1_HUMAN (1134-1593): 5.81e-11: 69.9: 9.62
+	Hs
		1176345 HECW1_HUMAN (2-222): 1.33e-24: 110: 14.96		MPP8_HUMAN (1152-1560): 6.19e-09: 63: 15.40
+	Hs
		1191736 HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79		RBBP6_HUMAN (1129-1593): 1.23e-11: 72.2: 12.29