HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: AJUBA (Q96IF1)
LIM domain-containing protein ajuba
Gene: AJUBA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25796446
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm and 2 others more... GO:0005829 - cytosol GO:0005911 - cell-cell junction
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 538
+	Hs
		808640 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		TRIP6_HUMAN (80-530): 6.56e-57: 199: 25.81
+	Hs
		816282 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		LIMS1_HUMAN (292-526): 1.32e-42: 156: 19.67
+	Hs
		125735 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		808847 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PDLI5_HUMAN (9-456): 1.16e-29: 125: 14.50
+	Hs
		1050798 SMUF2_HUMAN (99-504): 4.95e-107: 337: 19.19		FHL2_HUMAN (364-537): 2.12e-34: 132: 22.16
+	Hs
		1336088 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		1327916 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		808955 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		808283 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		808647 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		ZYX_HUMAN (22-391): 2.31e-09: 61.9: 16.83
+	Dm
		1115157 YAP1_DROME (52-268): 1.16e-44: 163: 29.25		AJUBA_DROME (27-529): 1.18e-70: 241: 32.60
+	Hs
		1076525 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		TRIP6_HUMAN (80-530): 6.56e-57: 199: 25.81
+	Hs
		1293394 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		PDLI5_HUMAN (9-456): 1.16e-29: 125: 14.50
+	Hs
		1076559 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		TRIP6_HUMAN (80-530): 6.56e-57: 199: 25.81
+	Hs
		1326752 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		1326768 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		LIMD1_HUMAN (14-536): 1.42e-19: 94.3: 14.99
+	Hs
		1274169 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		LPP_HUMAN (10-454): 6.46e-11: 67: 13.00
+	Hs
		1080775 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		ZYX_HUMAN (22-391): 2.31e-09: 61.9: 16.83
+	Hs
		1344053 WWC3_HUMAN (170-318): 1.24e-30: 128: 26.17		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89