HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: ACINU (Q9UKV3)
Apoptotic chromatin condensation inducer in the nucleus (Acinus)
Gene: ACIN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30472188, 38280479
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 1341
+	Hs
		808624 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PLEC_HUMAN (127-1331): 9.01e-66: 248: 13.03
+	Hs
		125817 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PRC2C_HUMAN (53-1307): 9.8e-44: 177: 8.48
+	Hs
		1349032 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		ACINU_HUMAN (1-1341): 5.71e-134: 447: 100.00
+	Hs
		125795 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		SRRM2_HUMAN (8-1253): 1.08e-39: 163: 10.40
+	Hs
		809056 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PRC2C_HUMAN (53-1307): 9.8e-44: 177: 8.48
+	Hs
		809031 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		SRRM2_HUMAN (8-1253): 1.08e-39: 163: 10.40
+	Hs
		125448 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		EIF3A_HUMAN (608-1307): 2.15e-25: 116: 9.34
+	Hs
		1049652 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		EIF3A_HUMAN (608-1307): 2.15e-25: 116: 9.34
+	Hs
		808598 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		EIF3A_HUMAN (608-1307): 2.15e-25: 116: 9.34
+	Hs
		808785 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		THOC2_HUMAN (949-1336): 6.77e-15: 82.5: 10.47
+	Dm
		1373179 SUDX_DROME (16-504): 4.46e-109: 347: 15.74		Q9VRM6_DROME (1125-1341): 3.99e-17: 89.8: 16.60
+	Hs
		1264807 SMUF2_HUMAN (99-504): 4.95e-107: 337: 19.19		TITIN_HUMAN (117-1066): 5e-19: 96.4: 11.38
+	Hs
		152609 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		KMT2D_HUMAN (137-637): 2.21e-12: 74.5: 12.87
+	Dm
		54898 SUDX_DROME (16-504): 4.46e-109: 347: 15.74		A1ZA72_DROME (233-1338): 1.97e-09: 64.7: 12.62
+	Hs
		1326806 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		PRC2C_HUMAN (53-1307): 9.8e-44: 177: 8.48
+	Hs
		152688 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		KMT2D_HUMAN (137-637): 2.21e-12: 74.5: 12.87
+	Hs
		203253 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		SYNJ1_HUMAN (350-777): 9.18e-11: 69.1: 8.65
+	Hs
		1049665 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		EIF3A_HUMAN (608-1307): 2.15e-25: 116: 9.34
+	Dm
		54872 YAP1_DROME (52-268): 1.16e-44: 163: 29.25		A1ZA72_DROME (233-1338): 1.97e-09: 64.7: 12.62