HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: FOXJ3 (Q9UPW0)
Forkhead box protein J3
Gene: FOXJ3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	35044719
Identification Methods	unspecified method, phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 622
+	Hs
		808319 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		FOXJ3_HUMAN (1-609): 1.54e-83: 276: 100.00
+	Mm
		93260 E9PXB7_MOUSE (8-504): 1.1e-114: 359: 19.11		FOXA2_MOUSE (71-359): 7.68e-48: 175: 22.92
+	Hs
		1016234 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		FOXO1_HUMAN (30-497): 1.86e-43: 167: 18.76
+	Hs
		808550 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		FOXO1_HUMAN (30-497): 1.86e-43: 167: 18.76
+	Hs
		808433 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		FOXA1_HUMAN (34-366): 6.72e-43: 162: 22.48
+	Hs
		808563 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		FOXI1_HUMAN (77-278): 3.35e-42: 158: 34.76
+	Hs
		808063 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		FOXA1_HUMAN (34-366): 6.72e-43: 162: 22.48
+	Hs
		808562 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		FOXC1_HUMAN (78-157): 6.35e-23: 104: 63.75
+	Hs
		1345879 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		FX4L1_HUMAN (16-326): 2e-48: 176: 23.90
+	Hs
		1021263 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		FOXI1_HUMAN (77-278): 3.35e-42: 158: 34.76
+	Hs
		964275 HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79		FOXK2_HUMAN (23-442): 7.69e-36: 145: 19.67