HitPredict

Interactor 1: YAP1 (P46938)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: WWTR1 (Q9EPK5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 16332960, 21145499
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains WW~WW
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001894 - tissue homeostasis
GO:0003015 - heart process
GO:0003713 - transcription coactivator activity
GO:0003714 - transcription corepressor activity
and 13 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 488
Mm

1 395
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024