HitPredict

Interactor 1: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Interactor 2: TES (Q9UGI8)
Testin (TESS)
Gene: TES

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 28378594
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0045296 - cadherin binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1657 Hs			1 421
+	Hs
		809210 IQGA1_HUMAN (1-1657): 0: 1732: 100.00		PAXI_HUMAN (298-421): 1.67e-35: 139: 22.58
+	Hs
		60124 A4QPB0_HUMAN (1-1657): 0: 1732: 99.94		PDLI7_HUMAN (358-421): 2.61e-09: 61: 26.56
+	Hs
		809448 IQGA1_HUMAN (1-1657): 0: 1732: 100.00		PDLI7_HUMAN (358-421): 2.61e-09: 61: 26.56
+	Hs
		823433 IQGA3_HUMAN (13-1657): 0: 1561: 58.87		PAXI_HUMAN (298-421): 1.67e-35: 139: 22.58
+	Hs
		596376 RASA1_HUMAN (459-1347): 4.15e-180: 571: 13.14		PAXI_HUMAN (298-421): 1.67e-35: 139: 22.58
+	Hs
		1189158 SYGP1_HUMAN (635-1477): 1.49e-108: 380: 12.26		PRIC2_HUMAN (296-421): 1.02e-26: 114: 20.61
+	Mm
		100030 SYGP1_MOUSE (635-1477): 1.84e-107: 376: 11.98		PRIC2_MOUSE (296-421): 5.88e-27: 115: 20.61
+	Dm
		1250311 GAP2_DROME (713-1391): 4.47e-91: 329: 13.21		ESN_DROME (301-421): 3.8e-27: 116: 21.43