HitPredict

Interactor 1: KCJ18 (B7U540)
Inward rectifier potassium channel 18 (Inward rectifier K(+) channel Kir2.6) (Potassium channel, inwardly rectifying subfamily J member 18)
Gene: KCNJ18

Interactor 2: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30126976
Identification Methods	p8 filamentous phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 433 Hs			1 904
+	Hs
		1021490 KCJ12_HUMAN (1-433): 0: 767: 98.61		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Rn
		852397 KCJ12_RAT (1-433): 0: 730: 94.46		DLG1_RAT (1-904): 0: 701: 92.54
+	Hs
		929764 KCNJ2_HUMAN (6-433): 0: 690: 70.00		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Rn
		1144015 KCNJ2_RAT (6-433): 0: 686: 70.23		DLG1_RAT (1-904): 0: 701: 92.54
+	Hs
		1054724 KCJ12_HUMAN (1-433): 0: 767: 98.61		DLG3_HUMAN (139-904): 0: 585: 66.28
+	Rn
		852399 KCJ12_RAT (1-433): 0: 730: 94.46		DLG3_RAT (99-904): 0: 590: 64.57
+	Hs
		1054729 KCJ12_HUMAN (1-433): 0: 767: 98.61		PALS2_HUMAN (421-899): 2.36e-108: 346: 23.48
+	Hs
		159210 KCJ12_HUMAN (1-433): 0: 767: 98.61		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Hs
		942342 KCJ12_HUMAN (1-433): 0: 767: 98.61		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Hs
		1049947 KCJ12_HUMAN (1-433): 0: 767: 98.61		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		1054723 KCJ12_HUMAN (1-433): 0: 767: 98.61		DLG2_HUMAN (393-627): 7.26e-21: 100: 24.48
+	Rn
		852398 KCJ12_RAT (1-433): 0: 730: 94.46		CSKP_RAT (19-362): 1.15e-28: 125: 12.26
+	Rn
		677769 KCJ12_RAT (1-433): 0: 730: 94.46		DLG4_RAT (86-493): 2.93e-24: 111: 15.40
+	Rn
		852400 KCJ12_RAT (1-433): 0: 730: 94.46		DLG2_RAT (393-627): 2.93e-21: 101: 24.48
+	Hs
		929762 KCNJ2_HUMAN (6-433): 0: 690: 70.00		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Hs
		929767 KCNJ2_HUMAN (6-433): 0: 690: 70.00		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Rn
		1144360 KCNJ2_RAT (6-433): 0: 686: 70.23		DLG2_RAT (393-627): 2.93e-21: 101: 24.48
+	Hs
		159173 KCNJ4_HUMAN (31-433): 0: 606: 63.12		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Mm
		852403 KCNJ4_MOUSE (32-433): 0: 618: 63.18		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Hs
		816146 KCNJ4_HUMAN (31-433): 0: 606: 63.12		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64