Interactor 1: SET2 (P46995)
Histone-lysine N-methyltransferase, H3 lysine-36 specific (EC 2.1.1.359) (Lysine N-methyltransferase 3) (SET domain-containing protein 2)
Gene: SET2
Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.947 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22343720, 12080090, 19379692, 19822661, 18923077, 16959570 |
| Identification Methods | methyltransferase assay, biochemical, affinity chromatography technology, pull down, enzymatic study |
| Interaction Type | direct interaction, physical association, enzymatic reaction, methylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AWS~Histone, Histone~SET |
| Common GO terms | GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
