HitPredict

Interactor 1: DAS1 (P47005)
F-box protein DAS1 (DST1-delta 6-azauracil sensitivity protein 1)
Gene: DAS1

Interactor 2: CDC53 (Q12018)
Cell division control protein 53 (Cullin-A) (E3 ubiquitin ligase complex SCF subunit CDC53)
Gene: CDC53

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.927

The method score is based on:

Property Details
Experiments 11283612, 11805837, 10582239, 14747994, 37968396
Identification Methods coimmunoprecipitation, anti tag coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~F-box-like
Common GO terms GO:0000409 - regulation of transcription by galactose
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
GO:0030674 - protein-macromolecule adaptor activity
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 663
Sc

1 815
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024