HitPredict

Interactor 1: MTR4 (P47047)
ATP-dependent RNA helicase DOB1 (EC 3.6.4.13) (mRNA transport regulator MTR4)
Gene: MTR4

Interactor 2: UTP4 (Q06679)
U3 small nucleolar RNA-associated protein 4 (U3 snoRNA-associated protein 4) (U three protein 4) (U3 protein 4 required for transcription) (t-UTP4)
Gene: UTP4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	26317469, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DSHCT~WD40
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1073 Sc			1 776
+	Sc
		635600 MTR4_YEAST (1-1073): 0: 819: 100.00		PWP2_YEAST (244-720): 2.31e-37: 152: 6.64
+	Hs
		786997 MTREX_HUMAN (51-1073): 0: 797: 51.42		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27
+	Hs
		254090 SKI2_HUMAN (10-1072): 0: 684: 32.47		WDR1_HUMAN (50-310): 6.11e-26: 115: 12.17
+	Hs
		1074495 SKI2_HUMAN (10-1072): 0: 684: 32.47		SKI8_HUMAN (116-293): 1.6e-13: 74.2: 21.79
+	Hs
		921639 DHX37_HUMAN (131-1043): 5.08e-99: 340: 12.98		GBB2_HUMAN (271-595): 3.16e-22: 100: 13.98
+	Hs
		903410 DDX17_HUMAN (62-648): 5.57e-94: 317: 12.11		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		571382 DDX5_HUMAN (37-603): 1.92e-94: 315: 12.25		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		1282711 DDX31_HUMAN (5-753): 1.5e-90: 311: 13.32		UTP4_HUMAN (410-699): 2.84e-20: 98: 8.48
+	Hs
		272085 U520_HUMAN (98-698): 2.82e-85: 306: 18.04		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		181727 DDX3Y_HUMAN (2-588): 1.75e-88: 300: 12.56		UTP4_HUMAN (410-699): 2.84e-20: 98: 8.48
+	Hs
		133956 DDX3X_HUMAN (8-588): 9.89e-89: 301: 12.62		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		1271621 DDX17_HUMAN (62-648): 5.57e-94: 317: 12.11		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27
+	Hs
		1271679 DDX17_HUMAN (62-648): 5.57e-94: 317: 12.11		NLE1_HUMAN (557-661): 1.4e-11: 69.5: 10.28
+	Hs
		571547 DDX5_HUMAN (37-603): 1.92e-94: 315: 12.25		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27
+	Hs
		181721 DDX3Y_HUMAN (2-588): 1.75e-88: 300: 12.56		POC1A_HUMAN (504-755): 5.79e-17: 85.7: 7.35
+	Hs
		1288310 DDX31_HUMAN (5-753): 1.5e-90: 311: 13.32		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27
+	Hs
		1333547 DDX31_HUMAN (5-753): 1.5e-90: 311: 13.32		NLE1_HUMAN (557-661): 1.4e-11: 69.5: 10.28
+	Hs
		272239 U520_HUMAN (98-698): 2.82e-85: 306: 18.04		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27
+	Hs
		1221908 DDX60_HUMAN (134-306): 8.62e-11: 68.6: 29.26		WDR3_HUMAN (275-595): 1.21e-20: 99.6: 17.13
+	Hs
		903282 DDX6L_HUMAN (134-306): 6.89e-09: 62.4: 28.19		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41