HitPredict

Interactor 1: NU192 (P47054)
Nucleoporin NUP192 (Nuclear pore protein NUP192)
Gene: NUP192

Interactor 2: NU116 (Q02630)
Nucleoporin NUP116/NSP116 (Nuclear pore protein NUP116/NSP116)
Gene: NUP116

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.703

Property	Details
Experiments	26344569, 18046405, 10684247, 29033133, 27194810
Identification Methods	pull down, affinity chromatography technology, biochemical, two hybrid array
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0006913 - nucleocytoplasmic transport GO:0006999 - nuclear pore organization GO:0017056 - structural constituent of nuclear pore
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1683 Sc			1 1113
+	Sc
		811033 NU192_YEAST (1-1683): 0: 1682: 100.00		NU145_YEAST (489-1108): 1.48e-68: 254: 23.15
+	Sc
		811041 NU192_YEAST (1-1683): 0: 1682: 100.00		NU100_YEAST (1-708): 2.45e-22: 106: 16.36
+	Sc
		541892 NU192_YEAST (1-1683): 0: 1682: 100.00		NSP1_YEAST (371-960): 3.45e-17: 89.3: 12.84
+	Sc
		811031 NU192_YEAST (1-1683): 0: 1682: 100.00		NUP57_YEAST (272-533): 3.69e-10: 65.9: 29.43
+	Sc
		811032 NU192_YEAST (1-1683): 0: 1682: 100.00		NUP42_YEAST (3-329): 6.21e-10: 65: 14.20
+	Sc
		774354 NU192_YEAST (1-1683): 0: 1682: 100.00		NU159_YEAST (4-454): 8.42e-09: 62.3: 10.53
+	Sc
		811039 NU192_YEAST (1-1683): 0: 1682: 100.00		NUP49_YEAST (168-386): 4.55e-09: 62.1: 29.92
+	Hs
		858020 NU205_HUMAN (23-1642): 0: 1308: 15.72		NUP98_HUMAN (2-615): 2.83e-37: 155: 18.40
+	Hs
		727298 NU205_HUMAN (23-1642): 0: 1308: 15.72		NU214_HUMAN (4-549): 7.13e-15: 82.3: 14.91
+	Hs
		834649 NU205_HUMAN (23-1642): 0: 1308: 15.72		NU153_HUMAN (5-423): 1.86e-10: 67.7: 12.56
+	Tt
		101882 NU192_CHATD (24-1644): 0: 1131: 20.07		NU145_CHATD (7-801): 6.29e-17: 88.9: 15.09
+	Tt
		101880 NU192_CHATD (24-1644): 0: 1131: 20.07		NUP49_CHATD (386-575): 5.34e-09: 62.1: 32.66
+	Hs
		857991 NU188_HUMAN (633-1341): 1.14e-87: 320: 13.16		NUP98_HUMAN (2-615): 2.83e-37: 155: 18.40
+	Hs
		727269 NU188_HUMAN (633-1341): 1.14e-87: 320: 13.16		NU214_HUMAN (4-549): 7.13e-15: 82.3: 14.91
+	Hs
		834612 NU188_HUMAN (633-1341): 1.14e-87: 320: 13.16		NU153_HUMAN (5-423): 1.86e-10: 67.7: 12.56