HitPredict

Interactor 1: MPP10 (P47083)
U3 small nucleolar RNA-associated protein MPP10 (U3 snoRNA-associated protein MPP10) (M phase phosphoprotein 10)
Gene: MPP10

Interactor 2: SAS10 (Q12136)
Something about silencing protein 10 (U three protein 3) (U3 small nucleolar RNA-associated protein 3) (U3 snoRNA-associated protein 11)
Gene: SAS10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.723

The method score is based on:

Property Details
Experiments 11283351, 29054886, 20884785, 12068309, 37968396
Identification Methods two hybrid pooling approach, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 3 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 593
Sc

1 610
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024