HitPredict

Interactor 1: LSM8 (P47093)
U6 snRNA-associated Sm-like protein LSm8
Gene: LSM8

Interactor 2: PRP31 (P49704)
Pre-mRNA-processing factor 31
Gene: PRP31

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	10747033, 37968396, 16429126
Identification Methods	biochemical, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0046540 - U4/U6 x U5 tri-snRNP complex GO:0071001 - U4/U6 snRNP and 1 others more... GO:0071011 - precatalytic spliceosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 109 Sc			1 494
+	Sc
		770315 RUXG_YEAST (2-69): 1.63e-17: 72.4: 21.62		PRP31_YEAST (1-494): 0: 590: 100.00
+	Sc
		830817 LSM7_YEAST (5-71): 3.29e-13: 62.3: 15.00		PRP31_YEAST (1-494): 0: 590: 100.00
+	Sc
		830819 LSM3_YEAST (5-76): 5.4e-10: 53.5: 22.22		PRP31_YEAST (1-494): 0: 590: 100.00
+	Hs
		912082 RUXG_HUMAN (3-69): 6.78e-25: 90.8: 20.29		PRP31_HUMAN (93-491): 1.06e-133: 397: 27.64
+	Hs
		68440 RUXGL_HUMAN (3-69): 6.48e-23: 85.8: 20.29		PRP31_HUMAN (93-491): 1.06e-133: 397: 27.64
+	Hs
		1263050 LSM7_HUMAN (5-81): 4.87e-19: 77: 17.24		PRP31_HUMAN (93-491): 1.06e-133: 397: 27.64
+	Hs
		927990 RSMN_HUMAN (2-64): 5.94e-17: 74.7: 20.00		PRP31_HUMAN (93-491): 1.06e-133: 397: 27.64
+	Hs
		539074 RSMB_HUMAN (2-64): 9.82e-17: 74.3: 20.00		PRP31_HUMAN (93-491): 1.06e-133: 397: 27.64