HitPredict

Interactor 1: ARP3 (P47117)
Actin-related protein 3 (Actin-like protein ARP3) (Actin-like protein 3)
Gene: ARP3

Interactor 2: CORO (Q06440)
Coronin-like protein
Gene: CRN1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	16554755, 21454476
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0030479 - actin cortical patch GO:0051015 - actin filament binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 449 Sc			1 651
+	Sc
		887686 ACT_YEAST (1-444): 0: 511: 32.44		CORO_YEAST (1-651): 8.36e-147: 442: 100.00
+	Hs
		892108 ACTB_HUMAN (1-444): 0: 520: 32.44		COR1C_HUMAN (3-487): 2.38e-92: 295: 36.33
+	Hs
		930051 ACTG_HUMAN (3-444): 0: 520: 32.36		COR1C_HUMAN (3-487): 2.38e-92: 295: 36.33
+	Hs
		932449 ACTC_HUMAN (2-444): 0: 515: 32.29		COR1C_HUMAN (3-487): 2.38e-92: 295: 36.33
+	Hs
		932355 ACTC_HUMAN (2-444): 0: 515: 32.29		COR1B_HUMAN (1-487): 4.21e-88: 285: 34.89
+	Hs
		896846 ARP3_HUMAN (7-449): 6.34e-172: 490: 58.35		COR1C_HUMAN (3-487): 2.38e-92: 295: 36.33
+	Hs
		891943 ACTB_HUMAN (1-444): 0: 520: 32.44		COR2A_HUMAN (1-477): 1.03e-78: 261: 36.81
+	Hs
		929956 ACTG_HUMAN (3-444): 0: 520: 32.36		COR2A_HUMAN (1-477): 1.03e-78: 261: 36.81
+	Hs
		884627 ACTB_HUMAN (1-444): 0: 520: 32.44		CORO7_HUMAN (7-431): 1.7e-67: 239: 26.62
+	Hs
		884629 ARP3_HUMAN (7-449): 6.34e-172: 490: 58.35		CORO7_HUMAN (7-431): 1.7e-67: 239: 26.62
+	Hs
		891660 ACTB_HUMAN (1-444): 0: 520: 32.44		WDR5_HUMAN (262-452): 3.45e-23: 102: 5.70
+	Hs
		903110 ACTG_HUMAN (3-444): 0: 520: 32.36		WDR5_HUMAN (262-452): 3.45e-23: 102: 5.70
+	Hs
		932318 ACTC_HUMAN (2-444): 0: 515: 32.29		SNR40_HUMAN (314-524): 2.37e-09: 61.7: 11.27