HitPredict

Interactor 1: ARP3 (P47117)
Actin-related protein 3 (Actin-like protein ARP3) (Actin-like protein 3)
Gene: ARP3

Interactor 2: AIM7 (Q12156)
Protein AIM7 (Altered inheritance rate of mitochondria protein 7)
Gene: AIM7

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.840

Property	Details
Experiments	23727094, 30042427, 20362448
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0030479 - actin cortical patch
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 449 Sc			1 149
+	Sp
		143278 ARP3_SCHPO (1-446): 0: 606: 68.01		GMF1_SCHPO (2-146): 2.96e-32: 113: 28.28
+	Hs
		891649 ACTB_HUMAN (1-444): 0: 520: 32.44		DEST_HUMAN (1-146): 3.33e-50: 159: 16.77
+	Hs
		894652 ACTG_HUMAN (3-444): 0: 520: 32.36		DEST_HUMAN (1-146): 3.33e-50: 159: 16.77
+	Hs
		894665 Q1KLZ0_HUMAN (1-444): 0: 520: 32.44		DEST_HUMAN (1-146): 3.33e-50: 159: 16.77
+	Hs
		618038 ACTB_HUMAN (1-444): 0: 520: 32.44		COF1_HUMAN (1-146): 3.06e-46: 149: 18.59
+	Hs
		618049 ACTG_HUMAN (3-444): 0: 520: 32.36		COF1_HUMAN (1-146): 3.06e-46: 149: 18.59
+	Hs
		618096 Q1KLZ0_HUMAN (1-444): 0: 520: 32.44		COF1_HUMAN (1-146): 3.06e-46: 149: 18.59
+	Hs
		1092828 Q1KLZ0_HUMAN (1-444): 0: 520: 32.44		Q549N0_HUMAN (1-146): 3.41e-45: 147: 19.87
+	Hs
		891817 ACTB_HUMAN (1-444): 0: 520: 32.44		Q549N0_HUMAN (1-146): 3.41e-45: 147: 19.87
+	Hs
		929891 ACTG_HUMAN (3-444): 0: 520: 32.36		Q549N0_HUMAN (1-146): 3.41e-45: 147: 19.87
+	Hs
		930059 ACTG_HUMAN (3-444): 0: 520: 32.36		COF2_HUMAN (1-146): 3.41e-45: 147: 19.87
+	Hs
		891650 ACTB_HUMAN (1-444): 0: 520: 32.44		GMFB_HUMAN (6-146): 8.85e-39: 129: 24.11
+	Hs
		894697 ACTG_HUMAN (3-444): 0: 520: 32.36		GMFB_HUMAN (6-146): 8.85e-39: 129: 24.11
+	Dm
		501443 ACT5_DROME (1-444): 0: 520: 32.22		CADF_DROME (1-147): 4.34e-22: 87.5: 13.82
+	Dm
		501459 ACT5_DROME (1-444): 0: 520: 32.22		Q9VWR1_DROME (1-148): 3.44e-21: 85.2: 14.10
+	Ce
		501473 ACT4_CAEEL (1-444): 0: 521: 32.44		ADF1_CAEEL (1-149): 3.36e-18: 79: 13.86
+	Hs
		891834 ACTB_HUMAN (1-444): 0: 520: 32.44		TWF2_HUMAN (13-149): 2.65e-11: 61.7: 19.42
+	Hs
		929897 ACTG_HUMAN (3-444): 0: 520: 32.36		TWF2_HUMAN (13-149): 2.65e-11: 61.7: 19.42
+	Hs
		891728 ACTB_HUMAN (1-444): 0: 520: 32.44		TWF1_HUMAN (3-146): 6.61e-10: 57.8: 17.12
+	Hs
		929835 ACTG_HUMAN (3-444): 0: 520: 32.36		TWF1_HUMAN (3-146): 6.61e-10: 57.8: 17.12