HitPredict

Interactor 1: VPS25 (P47142)
Vacuolar protein-sorting-associated protein 25 (ESCRT-II complex subunit VPS25)
Gene: VPS25

Interactor 2: VPS28 (Q02767)
Vacuolar protein sorting-associated protein 28 (ESCRT-I complex subunit VPS28)
Gene: VPS28

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.648

Property	Details
Experiments	16615894, 15086794, 18719252
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006623 - protein targeting to vacuole GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0043328 - protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:1904669 - ATP export
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 202 Sc			1 242
+	Hs
		1309994 VPS25_HUMAN (5-199): 4.42e-64: 197: 27.69		VPS28_HUMAN (16-241): 1.6e-94: 277: 29.83